Status:
ENROLLING_BY_INVITATION
Study of Brain Function Evaluation System for Acute and Prolonged Disorders of Consciousness
Lead Sponsor:
Xuanwu Hospital, Beijing
Collaborating Sponsors:
Tianjin University
Jilin University
Conditions:
Disorder of Consciousness
Eligibility:
All Genders
14-60 years
Brief Summary
The research focuses on establishing a system for detecting loss of consciousness, developing clinical prognostic and awakening-related brain function testing criteria.
Detailed Description
A framework for the acquisition of neural features, feature selection and mechanism analysis of consciousness deficits in patients with acute and prolonged disorders of consciousness(DOC). Based on th...
Eligibility Criteria
Inclusion
- Admission criteria for patients with prolonged disorders of consciousness
- Age 14-60 years;
- In accordance with the diagnostic criteria of unresponsive arousal syndrome or minimally conscious state by international research;
- Brain Trauma, stroke and hypoxic-ischemic encephalopathy lead to disturbance of consciousness;
- right-handed；
- The patient's family members signed the informed consent form;
Exclusion
- The history of mental illness and a history of hearing impairment;
- Intracranial arterial clamp, pacemaker and other metal implants;
- During the experiment, sedatives and other drugs that affect the excitability of the cortex;
- The presence of uncontrolled seizures or involuntary movements;
- Admission criteria for patients with acute disorders of consciousness
- Inclusion Criteria:
- (1)Age 14-60 years; (2）Meets diagnostic criteria for coma recognized in international studies； (3)the GCS score was less than 8; (4)Brain Trauma, stroke and hypoxic-ischemic encephalopathy lead to disturbance of consciousness; (5) right-handed； (6)The patient's family members signed the informed consent form;
Key Trial Info
Start Date :
April 13 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06097013
Start Date
April 13 2022
End Date
November 1 2026
Last Update
July 22 2024
Active Locations (1)
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1
Xuan Wu hospitial, capical medical university
Beijing, China