Status:
UNKNOWN
Prophylactic Oral Vitamin D and Zinc for Radiation-Induced Oral Mucositis in Head and Neck Cancer
Lead Sponsor:
Assiut University
Conditions:
Oncology
Eligibility:
All Genders
18+ years
Brief Summary
The main aim of this study was to evaluate clinically the effect of a combination between oral vitamin D and oral zinc in comparison to conventional therapy in prevention of radiotherapy-induced oral ...
Detailed Description
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity and l...
Eligibility Criteria
Inclusion
- Selection of patients
- All adults (18 years or older ), who were confirmed based on pathology ( Head and Neck Squamous Cell Carcinomas ), will administere chemo-radiotherapy either as preoperative (neoadjuvant), postoperative (adjuvant) therapy or definitive therapy, no randomization .
- The treatment group will receive combined oral Vit D and Zinc and the control group will take placebo capsules or receive no treatment.
- No documentation of any other causes of oral mucositis in their medical records as : immunocomprmized patients d.t HIV
Exclusion
- Non Head and Neck cancer
- patients with any other causes of oral mucositis
- Double malignancy
- Un eligible patients for radiotherapy ( comatosed, bedridden and sever chest disease )
Key Trial Info
Start Date :
November 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06100692
Start Date
November 1 2023
End Date
December 1 2024
Last Update
November 7 2023
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.