Status:
UNKNOWN
Effect of Physical Activity on Neurogenesis in Peripheral Diabetic Neuropathy Type-II Diabetes
Lead Sponsor:
Health Education Research Foundation (HERF)
Conditions:
Type II Diabetes Mellitus With Neurological Manifestations
Eligibility:
All Genders
45-60 years
Phase:
NA
Brief Summary
Approximately 425 million people worldwide suffer from diabetes, making it a global epidemic. Diabetes consumes 12% of the global health budget, addressing the disease and its complications. In Pakist...
Detailed Description
The study design is a randomized controlled trial, and participants will be blinded to avoid interaction. A convenience sampling technique will be used, and the study will take place at Pakistan Railw...
Eligibility Criteria
Inclusion
- Patients with Type-II Peripheral Diabetic Neuropathy
- Neuropathy Total Symptom Scale (NTSS-6)\>6
- loss of protective sensation to detect a 10-gram Semmes Weinstein Monofilament on either foot at one of four sites tested or a vibration perception threshold value of 25V or more at either foot's hallux
- Numbness or reduced ability to feel pain or temperature changes.
- Able to Perform 20 minutes per week \>2 bouts of physical activity
- Tingling or burning sensation.
- Sharp pains or cramps.
- Increased sensitivity to touch
- Symptoms last ≥ 6 months
- HbA1c above 6.5% \<12%
- Berg Balance Scale score 45-56
Exclusion
- Patients with walking difficulty
- Retinopathy \& poor vision
- Inability to engage in activity without assistance
- Peripheral vascular disease e.g. ABI \<0.6
- orthostatic hypotension, resting heart rate above 100 bpm any Cardiac Issues
- Any diagnosed neuro-psychological issue e.g. depression, dementia or anxiety
- Lower limb amputation,foot deformity or ulceration
- Acute injury
- Hip and Knee OA
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2025
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT06101368
Start Date
January 1 2024
End Date
March 31 2025
Last Update
October 26 2023
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.