Status:
COMPLETED
Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication
Lead Sponsor:
Ain Shams University
Conditions:
Helicobacter Pylori Eradication
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
This trial assessed the efficacy of potassium competetor acid blocker (P-CAB) in the eradication of H.pylori
Detailed Description
The aim of this study is to compare the effectiveness of Vonaprazan based therapy vs.Proton Pump Inhibitor (PPI)based therapy for the eradication of H.Pylori infection in treatment naive and treatment...
Eligibility Criteria
Inclusion
- Age above 18 years of both genders.
- Symptomatic patients who has been diagnosed to be H. pylori positive stool by using H. pylori stool antigen test.
- Patients who did not receive H. pylori eradication regimens before were included in group I of the study (First line eradication regimen).
- Patients who received only one eradication regimen before were included in group II of the study (Second line eradication regimen).
- Patients signing an informed consent.
Exclusion
- Patients refusing to sign an informed consent.
- Patients who were on PPIs, P-CABs and/or antibiotics starting one month before inclusion in the study .
- Patients who have chronic debilitating and advanced systemic diseases.
- Patients treated with low dose aspirin and/or non-steroidal anti-inflammatory drugs for a long time.
- Any lactating or pregnant female.
Key Trial Info
Start Date :
January 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2023
Estimated Enrollment :
232 Patients enrolled
Trial Details
Trial ID
NCT06101420
Start Date
January 1 2022
End Date
June 1 2023
Last Update
October 26 2023
Active Locations (1)
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1
Faculty of Medicine Ain Shams University
Cairo, Egypt, 11341