Status:
UNKNOWN
Ultrasound Assessment of Sarcopenia in Patients With Chronic Liver Disease: the SARCOLIVER Study
Lead Sponsor:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions:
Liver Cirrhosis
Non-Alcoholic Fatty Liver Disease
Eligibility:
All Genders
18-69 years
Phase:
NA
Brief Summary
Sarcopenia is a complex multifactorial syndrome which could be present in older age (primary sarcopenia) or earlier in chronic disease (secondary sarcopenia). Even if in patients with chronic liver di...
Eligibility Criteria
Inclusion
- Ability to express informed consent
- Diagnosis of liver cirrhosis or non-alcoholic fatty liver disease or hepatocellular carcinoma based on clinical characteristics, biochemical serum tests and liver imaging examination or liver histologic examination if available
Exclusion
- inability to express informed consent
- pregnancy
- presence of a concomitant oncologic disease different from hepatocellular carcinoma
- presence of a concomitant gastrointestinal disease able to influence the absorption and digestion of nutrients (e.g. inflammatory bowel disease, celiac disease, short-bowel syndrome, congenital defects of metabolism)
- presence of a concomitant gastrointestinal or neurologic disease able to influence the ability of feeding (e.g. dysphagia, parkinson disease, neuromuscular diseases, diseases of the autonomic nervous system, cognitive impairment or dementia)
- chronic kidney disease from stage 3 B (IIIB) according to Kidney Disease: Improving Global Outcomes (KDIGO) classification (eGFR \<45ml/min/1.73m2)
- chronic heart failure from stage Ney York Heart Association (NYHA) II
- concomitant infection from Mycobacterium Tuberculosis or human immunodeficiency virus or chronic parasitic infections
Key Trial Info
Start Date :
October 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT06101758
Start Date
October 20 2023
End Date
July 1 2025
Last Update
October 26 2023
Active Locations (1)
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1
CEMAD
Roma, RM, Italy, 00168