Status:
RECRUITING
Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Lead Sponsor:
Rigshospitalet, Denmark
Collaborating Sponsors:
University of Copenhagen
Conditions:
Ischemic Heart Disease
Non STEMI
Eligibility:
All Genders
Phase:
NA
Brief Summary
Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes. However, there is limited evidence supporti...
Eligibility Criteria
Inclusion criteria:
- Admitted with non-ST-segment elevation myocardial infarction or unstable angina pectoris and an indication for subacute ICA
- Elevated troponin or ischemic electrocardiographic changes
- Written informed consent
Exclusion criteria:
- Instability requiring acute or emergent ICA
- History of percutaneous coronary intervention or coronary artery bypass grafting
- Estimated glomerular filtration rate < 30 mL/min/1.73m2
- Probable type 2 acute myocardial infarction
- Severe valvular heart disease as primary diagnosis or potential need for valve intervention
- History of spontaneous coronary artery dissection
- Expected poor quality of the CCTA
- Prior CCTA or ICA during index admission or within 1 week
- Known allergy to beta-blockers or contrast agent
- Pregnant or nursing
- Previously randomized in this trial
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2036
Estimated Enrollment :
2300 Patients enrolled
Trial Details
Trial ID
NCT06101862
Start Date
October 1 2023
End Date
October 1 2036
Last Update
February 19 2025
Active Locations (6)
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1
Herlev and Gentofte Hospital
Copenhagen, Hellerup, Denmark, 2900
2
Bispebjerg Hospital
Bispebjerg, Denmark
3
Rigshospitalet
Copenhagen, Denmark
4
Zealand University Hospital
Copenhagen, Denmark