Status:
UNKNOWN
Identification of Biomarkers in Subjects With Coronary Syndrome (PLAQUE Study)
Lead Sponsor:
Istituto Nazionale di Ricovero e Cura per Anziani
Collaborating Sponsors:
Ministry of Health, Italy
Conditions:
Coronary Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
The study will to test the levels of innovative biomarkers, such as miRNAs, in the blood of subjects underwent to angioplasty procedure according to standard clinical practice.
Detailed Description
Twenty patients with acute coronary syndrome from non-ST-segment elevation myocardial infarction or with chronic coronary syndrome with clinical indication and favorable anatomy for coronary angioplas...
Eligibility Criteria
Inclusion
- Clinical indication for the PCI procedure according to the latest ESC (European Society of Cardiology) Guidelines
- Coronary stenosis treated with angioplasty must be located in the proximal segments of the three main vessels: IVA, CX and CD
- The vessels must have a diameter of their mid-distal section ≥ 3 mm
- Patients with NSTEMI ACS and clinical indication with favorable anatomy for coronary angioplasty, also called percutaneous coronary intervention (PCI), (for the ACS group)
- Patients with clinically incipient SCC with stable angina (or significant anginal equivalents) and clinical indication with favorable anatomy for PCI (for the SCC group)
Exclusion
- Contraindications to anticoagulant/antiplatelet therapy
- Extensive calcifications and/or tortuosity of the major epicardial segments
- Evidence of thrombotic occupation
- Patients with hemodynamic instability
- Patients with EF (ejection fraction) \< 35%
- Patients with severe chronic renal failure (e-GFR \< 30 mL/min)
Key Trial Info
Start Date :
March 6 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06103357
Start Date
March 6 2023
End Date
April 30 2024
Last Update
March 5 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
IRCCS INRCA Hospital
Ancona, Italy