Status:
RECRUITING
Second Phase of the Pilot Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women
Lead Sponsor:
Instituto Valenciano de Infertilidad, IVI VALENCIA
Conditions:
Infertility, Female
Oocyte Maturation
Eligibility:
FEMALE
18-35 years
Phase:
NA
Brief Summary
In vitro maturation (IVM) is a technique for obtaining potentially fertilizable oocytes from immature oocytes. An oocyte must be mature both nuclearly and cytoplasmically in order to be competent in t...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Women between 18-35 years old who have belonged to the egg donation program. Donors who agree to participate in the study after informing and signing the Informed Consent.
- Documented previous good response to ovarian stimulation (at least 10 total oocytes and/or 8 MII).
- Donors with at least one previous donation cycle, in which all oocytes obtained were freshly fertilized.
- Donors who have already done all their donation cycles allowed by law. No personal or family history of interest.
- From the medical point of view:
- Body mass index between 18-25 kg/m2. Normal uterus and ovaries, without organic pathology. No polycystic ovaries Antral follicle count (AFC) \>12 in the sum of the two ovaries on day 2-3 of the menstrual cycle. Normal karyotype Negative screening for infectious diseases (Hepatitis B virus, Hepatitis C virus, Human Immunodeficiency Virus and Syphilis). General analysis with hemogram, hemostasis and biochemistry with parameters within normality.
- Exclusion criteria:
- Any systemic or metabolic disorder that contraindicates the use of gonadotropins.
- Any medical condition that implies non-inclusion in the oocyte donation program.
- Taking hormonal contraceptives within the last 3 months.
Exclusion
Key Trial Info
Start Date :
February 28 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06103383
Start Date
February 28 2023
End Date
December 31 2024
Last Update
March 12 2024
Active Locations (1)
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1
Ivi Valencia
Valencia, Spain, 46015