Status:
RECRUITING
Siderophore-labelled Positron Emission Tomography for Correlating Invasive Fungal InfeCtions
Lead Sponsor:
Peter MacCallum Cancer Centre, Australia
Conditions:
Invasive Fungal Infections
Eligibility:
All Genders
18+ years
Brief Summary
This trial will demonstrate localised uptake of a radiolabelled fungal component (siderophore) in areas of known specific invasive fungal (Aspergillus) infection.
Detailed Description
This open label, single centre, proof of concept pilot imaging trial will evaluate technique for the diagnosis of invasive Aspergillus infection. It aims to demonstrate uptake of the gallium-sideropho...
Eligibility Criteria
Inclusion
- Patient has provided written informed consent
- Aged 18 years or older at written informed consent
- Within 2 weeks of proven or probable or possible invasive fungal infection (IFI) diagnosis as per EORTC criteria
- Imaging consistent with invasive pulmonary aspergillosis on CT or FDG-PET/CT with lesions at least 8mm in diameter
- Patient is willing and able to comply with the protocol for the duration of the study including scheduled visits such as follow up
Exclusion
- Women who are pregnant or lactating.
- Iron infusion within one week prior to scan
Key Trial Info
Start Date :
December 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2027
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06105411
Start Date
December 1 2023
End Date
April 1 2027
Last Update
September 5 2025
Active Locations (1)
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1
Peter MacCallum Cancer Centre
Melbourne, Victoria, Australia, 3000