Status:
RECRUITING
ADIE-FS - Aligning Dimensions of Interoceptive Experience in Patients With Functional Seizures
Lead Sponsor:
University College, London
Collaborating Sponsors:
Columbia University
Conditions:
Psychogenic Nonepileptic Seizures
Dissociative Seizures
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Functional seizures are common and harmful. They look like epileptic seizures but are not caused by the excess electrical discharges in the brain that arise in epilepsy. Our understanding of the mecha...
Detailed Description
Functional seizures are common and harmful. They look like epileptic seizures but are not caused by the excess electrical discharges in the brain that arise in epilepsy. Recent research by our and oth...
Eligibility Criteria
Inclusion
- Aged over 18 years
- Capacity to complete informed consent to take part in study
- Possible, or probable or clinically established or documented functional seizure as per International League Against Epilepsy (ILAE) criteria
Exclusion
- Age below 18 years
- Past moderate to severe head injury as defined by Mayo criteria
- Moderate to severe cognitive impairment
- Co-existing or past neurological disorder causing sensorimotor symptoms
- Co-existing major psychiatric disorder with active psychosis
- Moderate to severe musculo-skeletal disease (e.g., osteoarthritis or rheumatoid arthritis) causing functional impairment (e.g., in gait or basic activities of daily living)
- Current substance or alcohol dependence
- A recent cardiovascular event (last 12 months) or undiagnosed chest pain
- BMI (body mass index \> 40kg/m2)
- Taking cardiac ionotropic drugs
- Uncontrolled hypertension
- Pregnancy
- Uncontrolled asthma or COPD (chronic obstructive pulmonary disease)
- Are having cognitive behavioural therapy (CBT) specifically for functional seizures, or are due to have CBT specifically for functional seizures within the period of the study.
Key Trial Info
Start Date :
January 10 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06105996
Start Date
January 10 2024
End Date
May 1 2024
Last Update
March 4 2024
Active Locations (1)
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1
Queen Square Institute of Neurology
London, United Kingdom, WC1N 3BG