Status:

UNKNOWN

Balloon-occluded Retrograde Transvenous Obliteration for Gastric Variceal Rebleeding

Lead Sponsor:

Kaohsiung Veterans General Hospital.

Conditions:

Gastric Varices Bleeding

Liver Decompensation

Eligibility:

All Genders

20+ years

Phase:

PHASE3

Brief Summary

The goal of this randomized controlled trial is to compare the rebleeding rate in cirhotic patients with gastric variceal bleeding receiving balloon-occluded retrograde transvenous obliteration and en...

Detailed Description

Variceal bleeding is a severe complication of portal hypertension. Gastric variceal bleeding (GVB) is more severe than bleeding from esophageal varices. Gastric varices also have a higher risk of rebl...

Eligibility Criteria

Inclusion

  • age more than 20 years
  • a history of liver cirrhosis
  • acute GOV2 or IGV1 bleeding

Exclusion

  • previous treatment for gastric varices, including endoscopic therapy, transjugular intrahepatic portosystemic shunt, or shunt surgery
  • hepatocellular carcinoma or other malignancy
  • stroke, uremia, or active sepsis
  • serum total bilirubin \>10 mg/dL
  • grade III/IV hepatic encephalopathy
  • refractory ascites
  • uncontrolled index bleeding
  • pregnancy
  • severe heart failure (NYHA Fc III/IV)
  • allergy to cyanoacrylate, lipiodol, iodine, or sodium tetradecyl sulfate
  • absence of gastrorenal shunt

Key Trial Info

Start Date :

June 28 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2025

Estimated Enrollment :

68 Patients enrolled

Trial Details

Trial ID

NCT06106971

Start Date

June 28 2018

End Date

June 1 2025

Last Update

October 30 2023

Active Locations (1)

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Kaohsiung Veterans General Hospital

Kaohsiung City, Taiwan, 813