Status:
UNKNOWN
High Versus Low Dose Nitroglycerin in Acute Pulmonary Edema
Lead Sponsor:
Alexandria University
Conditions:
Pulmonary Edema
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The goal of this randomized controlled trial is evaluate the out come of: * Low dose (\< 100 mic/min )versus * High dose (\> 100 mic/min) of nitroglycerin in management of patients with acute pulmona...
Detailed Description
This single blind parallel randomized controlled trial will be conducted on (30 patients in each group) presented to Alexandria University Hospitals with acute pulmonary edema defined as: acute onset ...
Eligibility Criteria
Inclusion
- All adult patients (\> 18 years) presented with sympathetic crashing acute pulmonary edema.
Exclusion
- 1 - Patients indicated for emergency endotracheal intubation. 2-Patients with history of nitroglycerin allergy. 3-Preload dependent patients as patients with aortic stenosis. 4-Drug interaction with nitroglycerin as sildenafil, ergots. 5-Patients indicated for emergency percutaneous intervention.
Key Trial Info
Start Date :
November 10 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06107465
Start Date
November 10 2023
End Date
July 1 2024
Last Update
October 30 2023
Active Locations (1)
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1
Alexandria University, Faculty of Medicine
Alexandria, Egypt