Status:
RECRUITING
Using Electrical Impedance Tomography to Investigate the Relationship Between Airflow Rate During High-flow Oxygen Therapy and Pressure in Patients With Heart Failure Compared to Non-invasive Ventilation
Lead Sponsor:
National Taiwan University Hospital
Conditions:
to Assess the Corresponding PEEP Values in NIV With CPAP Under Different Airflow Rates During HFOT in Heart Failure Patients
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Non-invasive ventilation (NIV) has been widely used in heart failure patients with supporting evidence. However, the drawbacks and contraindications associated with NIV limit its applicability in cert...
Detailed Description
Non-invasive ventilation (NIV) has been widely used in heart failure patients with supporting evidence. However, the drawbacks and contraindications associated with NIV limit its applicability in cert...
Eligibility Criteria
Inclusion
- Patients in the intensive care unit (ICU) with PaO2/FiO2 ≤ 300, requiring Non-Invasive Ventilation (NIV) and High-Flow Oxygen Therapy (HFOT) and stable use of NIV and HFOT for at least 24 hours will be eligible for enrollment.
- Evidence of pulmonary infiltrates on chest X-ray in patients with heart failure.
- Alert and able to follow instructions.
Exclusion
- Age \< 18 years.
- Patients with a history of tracheostomy.
- Hemodynamically unstable (defined as a mean arterial pressure persistently below 60 mmHg despite fluid resuscitation or vasopressor support).
- Severe chronic obstructive pulmonary disease (COPD).
- History of nasal trauma and/or nasal septal deviation or any other reason preventing the use of High-Flow Oxygen Therapy (HFOT).
- Presence of facial wounds or any other reason preventing the use of Non-Invasive Ventilation (NIV).
- Contraindications to Electrical Impedance Tomography (EIT) use (e.g., patients with implanted pacemakers) or inability to place EIT belt (e.g., due to wound dressings or chest drainage).
Key Trial Info
Start Date :
November 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06107907
Start Date
November 15 2023
End Date
March 1 2025
Last Update
October 18 2024
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100