Status:

ENROLLING_BY_INVITATION

Long-term Follow-up of Participants Dosed with an Investigational Gene Editing Therapy for Cardiovascular Disease

Lead Sponsor:

Verve Therapeutics, Inc.

Conditions:

Atherosclerotic Cardiovascular Disease

Heterozygous Familial Hypercholesterolemia

Eligibility:

All Genders

18+ years

Brief Summary

LTF-001 is a long-term follow-up study of participants who received an investigational gene-editing therapy developed by the sponsor to evaluate the long-term effects of the investigational therapy. P...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • A participant has completed or discontinued from a Verve sponsored clinical study in which they received at least one dose of study drug.
  • A participant has provided informed consent for LTF-001.
  • Exclusion Criteria: N/A

Exclusion

    Key Trial Info

    Start Date :

    June 9 2024

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    October 1 2039

    Estimated Enrollment :

    116 Patients enrolled

    Trial Details

    Trial ID

    NCT06112327

    Start Date

    June 9 2024

    End Date

    October 1 2039

    Last Update

    November 27 2024

    Active Locations (3)

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    Page 1 of 1 (3 locations)

    1

    Clinical Study Center

    Auckland, New Zealand

    2

    Clinical Study Center

    Christchurch, New Zealand

    3

    Clinical Study Center

    London, United Kingdom