Status:
ENROLLING_BY_INVITATION
Olfactory Training in Various Populations
Lead Sponsor:
University of Kansas Medical Center
Conditions:
Olfactory Disorder
Smell Disorder
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
To date, there is no validated pharmacotherapy for olfactory disorders. Interestingly, olfactory training - the intentional exposure to odorants for the purposes of retraining the sense of smell - has...
Detailed Description
Study Objectives: The overall, primary goals of these studies are as follows: 1. To compare the outcomes of our olfactory testing battery for olfactory training to the previously published literature...
Eligibility Criteria
Inclusion
- Age 18-80
- Quantifiable or subjective olfactory dysfunction
- ability to complete objective olfactory tests and comply with olfactory training protocol
Exclusion
- Anyone lower than the age of 18, or greater than the age of 80
- Pregnant women, as sinonasal symptoms and changes in smell can occur in pregnancy and are multifactorial
- Patients with poor or questionable compliance, as participation requires daily compliance with study protocol
- Patient's that are unable to perform routine follow-up
- Patients who are participating in another study during this trial
- Patients with dementia, Alzheimer's disease, Parkinson's disease, or other neurocognitive disorders, as these conditions are associated with baseline olfactory dysfunction.
- Patients with other systemic conditions known to impact the sinonasal cavity such as Wegener's granulomatosis, Churg Strauss, and immunodeficiency, as their impact on olfaction is unknown
- Patients who are allergic to any of the smells or components of our olfactory testing and training
Key Trial Info
Start Date :
February 13 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2026
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT06115291
Start Date
February 13 2020
End Date
July 31 2026
Last Update
July 28 2025
Active Locations (1)
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1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160