Status:
UNKNOWN
Comparison of Dopamin Level in Idiopathic Parkinson's Patients
Lead Sponsor:
Ankara Ataturk Sanatorium Training and Research Hospital
Conditions:
Parkinson Disease
Treatment Adherence
Eligibility:
All Genders
40-75 years
Phase:
PHASE4
Brief Summary
Our primary aim is to compare the change in blood dopamine levels with a single dose of these two drugs in patients with unilateral findings or axial involvement. Our study aims to obtain guiding data...
Detailed Description
After more than 40 years of routine clinical use, levodopa has remained the gold standard of symptomatic efficacy in the treatment of Parkinson's disease (PD). Levodopa benserazide and levodopa carbid...
Eligibility Criteria
Inclusion
- Idiopathic parkinson disease with early stage unilateral manifestations or axial involvement (hoehn yahr stage 1 and 1.5)
- 40-75 years old years
- Not taking levodopa preparations in the last 12 hours
- Not having eaten for at least 2 hours
- Agreeing to participate in the study
Exclusion
- Patients under 40 years of age and over 75 years of age
- Taking levodopa preparations in the last 12 hours
- Having bilateral, axial involvement
- Having postural abnormalities
- Having balance disorders (Hoehn yahr stage 3 and above)
- Having eaten at least 1 hour ago
- Not agreeing to participate in the study
- Body mass index of 35 kg/m2 and above
- Use of apomorphine, levodopa/carbidopa intestinal gel
- Applying deep brain stimulation treatment
- Using a daily dose of levodopa over 800 mg
- Having dyskinesia
- Drug-induced parkinsonism
- Pregnant, postpartum and breastfeeding mothers
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2025
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT06115538
Start Date
October 1 2023
End Date
April 30 2025
Last Update
November 28 2023
Active Locations (1)
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1
Ankara Atatürk Sanatorium Training and Research Hospital
Ankara, Turkey (Türkiye), 063000