Status:

RECRUITING

fNIRS Study of Effort-dependent Brain Activations During Pointing Movements of the Upper Limb in Post-stroke Patients and Healthy Subjects

Lead Sponsor:

Clinique Les Trois Soleils

Collaborating Sponsors:

Centre Hospitalier Régional d'Orléans

Conditions:

Stroke

Healthy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Background: Following a stroke, as part of neurorehabilitation, the intensity of effort is important to promote neural changes and stimulate motor recovery. There are few studies concerning the cortic...

Detailed Description

Upper limb paresis is the most common motor deficit following a stroke, and its long-term persistence has an impact on patients' functional recovery and quality of life. Rehabilitation is therefore a ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA
  • For stroke subjects
  • Age ≥18 years;
  • Stroke-induced hemiparesis, chronic phase (\>6 months post-stroke);
  • Moderate upper limb paresis defined by an upper limb FMA score 20 pts \< FMA score \< 47 pts ;
  • Right-handed patient;
  • Patient having agreed to sign an informed consent form;
  • Patient affiliated to the French social security system.
  • For healthy subjects
  • Age-matched participant, for each stroke subject included will be associated a control subject of the same age (to the nearest 5 years);
  • Right-handed participant;
  • Participant having agreed to sign an informed consent form;
  • Participant affiliated to the French social security system.
  • NON-INCLUSION CRITERIA
  • For stroke subjects
  • Cognitive impairment making participation in the study impossible;
  • Phasic disorders preventing comprehension of instructions and effective communication.
  • For healthy subjects
  • Pathology of the dominant upper limb;
  • Cognitive disorders making participation in the study impossible;
  • Presence of labelled or unlabelled neurological disorders;
  • Persons under legal protection.

Exclusion

    Key Trial Info

    Start Date :

    January 15 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    March 1 2025

    Estimated Enrollment :

    56 Patients enrolled

    Trial Details

    Trial ID

    NCT06116006

    Start Date

    January 15 2024

    End Date

    March 1 2025

    Last Update

    January 22 2024

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    La Clinique Les Trois Soleils

    Boissise-le-Roi, France, 77310

    fNIRS Study of Effort-dependent Brain Activations During Pointing Movements of the Upper Limb in Post-stroke Patients and Healthy Subjects | DecenTrialz