Status:
UNKNOWN
Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp
Lead Sponsor:
Cairo University
Conditions:
Necrotic Pulp
Post Operative Pain
Eligibility:
All Genders
20-40 years
Phase:
PHASE4
Brief Summary
The aim of this study is to assess the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction.
Detailed Description
Clinical compare the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction when used as root canal irrigant in necr...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Systemically healthy patient (ASA I, II).
- Age between 20 and 40 years.
- Male or female.
- Patient who is able to sign and comprehend the pain scale (committed patient).
- Mandibular single rooted premolars having the following criteria:
- With single root canal.
- Diagnosed clinically with pulp necrosis.
- Absence of spontaneous pulpal pain.
- Positive pain on percussion denoting apical periodontitis.
- Slight widening of periodontal space or peri-apical radiolucency smaller than 3 mm (0-2mm).
- Exclusion criteria:
- Medically compromised patients (ASA III or IV).
- Teeth with:
- Immature roots.
- Vital pulp tissues.
- Association with swelling.
- Acute peri-apical abscess or acute exacerbation of a chronic abscess.
- Mobility Grade II or III.
- Previously accessed or endodontically treated.
- Deep periodontal pockets more than 4 mm.
- Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.
- Patients who could not interpret the NRS.
- Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women will be also excluded.
- History of intolerance to NSAIDs.
Exclusion
Key Trial Info
Start Date :
November 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT06116214
Start Date
November 1 2023
End Date
December 1 2024
Last Update
November 3 2023
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