Status:
UNKNOWN
Modifying Working Memory With Brain Stimulation
Lead Sponsor:
Maastricht University
Conditions:
Cardiac Arrest
Cognitive Impairment
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The investigators want to investigate the effect of rTMS on working memory measured by the N-back task. This is a single case experimental design, ABAB.
Detailed Description
Rationale: The survival rate of patients after cardiac arrest and resuscitation has increased considerably. A common consequence of cardiac arrest is ischemic-hypoxic brain damage leading to cognitive...
Eligibility Criteria
Inclusion
- Had a cardiac arrest between 3 months and 5 years prior to the experiment session.
- Scores lower than the general population (corrected for age, education, and sex) on at least one of the cognitive tests ( SD \< -1 on the Stroop, digit span, or TMT).
- Age 18 up to and including 75.
- Proficient in Dutch or English to understand the instructions for the N-back task.
- Has sufficient understanding to perform the N-back task.
- Written informed consent
Exclusion
- Has a pacemaker or ICD (implantable cardioverter-defibrillator)
- A history or a family member with a history of seizures / epilepsy (asked on the phone and checked on the first appointment).
- Metal implants in or near the head.
- Pregnancy
- Any other neurological disorder impending working memory performance besides the OHCA.
Key Trial Info
Start Date :
November 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2024
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT06119620
Start Date
November 1 2023
End Date
October 1 2024
Last Update
November 7 2023
Active Locations (1)
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1
Maastricht University
Maastricht, Limburg, Netherlands