Status:
UNKNOWN
Prediction of UA/SOD Ratio as a Biomarker of Oxidative Stress in Atrial Fibrillation
Lead Sponsor:
Yinglong Hou
Conditions:
Atrial Fibrillation
Hyperuricemia
Eligibility:
All Genders
18-90 years
Brief Summary
To clarify the predictive effects of uric acid and superoxide dismutase as biomarkers of oxidative stress on atrial fibrillation, and to provide greater value for the diagnosis and prediction of atria...
Detailed Description
In recent years, a growing number of reports have shown the importance of oxidative stress in the pathophysiological mechanism of AF. During oxidative stress, there is an imbalance between the product...
Eligibility Criteria
Inclusion
- This retrospective study enrolled all hospitalized patients from January 2018 to December 2020 at the Department of Cardiology in The First Affiliated Hospital of Shandong First Medical University. The diagnosis of AF was based on 12-lead electrocardiography (ECG) or 24-hour Holter monitoring, and classification was based on the published 2020 ESC guidelines for the diagnosis and management of AF.
Exclusion
- acute heart failure and acute myocardial infarction;
- severe liver or kidney dysfunction (with aspartate aminotransferase or alanine aminotransferase levels three times higher than normal and estimated glomerular filtration rate \<30 ml/ (min\*1.73 m2));
- malignant tumors;
- missing data of laboratory indicators at baseline.
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2024
Estimated Enrollment :
10000 Patients enrolled
Trial Details
Trial ID
NCT06119802
Start Date
January 1 2022
End Date
April 30 2024
Last Update
November 7 2023
Active Locations (1)
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1
Shandong provincal Qianfoshan hospital
Jinan, Shandong, China, 250014