Status:
UNKNOWN
Molecular Mechanisms Underpinning Sarcopenic Obesity
Lead Sponsor:
The Swedish School of Sport and Health Sciences
Conditions:
Sarcopenic Obesity
Obesity
Eligibility:
All Genders
18-80 years
Brief Summary
The coexistence of obesity and sarcopenia results in sarcopenic obesity, a high-risk geriatric condition associated with metabolic perturbations and several co-morbidities. Despite the rising numbers ...
Eligibility Criteria
Inclusion
- Body fat % in accordance with previously defined criteria
- Free of smoking (since 10 years)
- Able to walk without assistance
- Able to perform bilateral leg extension exercise
Exclusion
- History of or present disease of myocardial, vascular, endocrine, hepatic, renal, pulmonary or neuromuscular origin
- Uncontrolled hypo/hypertension
- Use of anticoagulants (Warfarin, Trombyl)
- Use of metformin or other anti-diabetic medications
- Poor appetite and unexplained weight loss (4,5 kg) over the past 6 months
- Active malignancy
- Present infection
- Dementia or delirium
- Other conditions that may interfere with the study protocol in the opinion of the PI
Key Trial Info
Start Date :
January 28 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06120647
Start Date
January 28 2020
End Date
December 30 2025
Last Update
December 11 2023
Active Locations (1)
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1
The Swedish School of Sport and Health Sciences
Stockholm, Sweden, 11433