Status:
RECRUITING
Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging
Lead Sponsor:
University of Kansas Medical Center
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Exercise Training
Aging
Eligibility:
All Genders
45-65 years
Phase:
NA
Brief Summary
The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement...
Detailed Description
The proposed project will target regulation and reward systems using guided imagery to increase exercise adherence by increasing positive affect and the evaluation of future rewards among mid-life adu...
Eligibility Criteria
Inclusion
- speak English
- have access to reliable communication (a telephone or cell phone, computer, etc.)
- normal or corrected to normal vision and hearing
- ambulatory (without the use of assistive devices)
- physically underactive
- able to give informed consent
- able to exercise continuously on the recumbent stepper exercise device for 4 minutes greater than or equal to 25 watts to demonstrate ability to perform exercise on stepper \& no aerobic exercise contraindications or other safety/physical concerns
- able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions
- stable blood pressure and statin medication doses for 30 days as these affect vascular health/hemodynamics
- willing and able to safely enter magnetic resonance (MR) scanner and attempt the MR scan
- willing and able to attempt a blood draw
Exclusion
- patients with arrhythmias or acute cardiac events will be excluded due to potential complications with the supervised moderate exercise
- at risk for hazard due to magnetic fields due to MR safety concerns
- have any neurologic or psychiatric disorder except depression, anxiety (including post-traumatic stress disorder)
- have history of seizures or head trauma due to MR data quality
Key Trial Info
Start Date :
February 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT06123182
Start Date
February 23 2024
End Date
May 1 2027
Last Update
April 15 2025
Active Locations (1)
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1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160