Status:
COMPLETED
Laser Visual Internal Urethrotomy With Versus Without Paclitaxel Injection
Lead Sponsor:
Ain Shams University
Conditions:
Urethral Stricture, Male
Eligibility:
MALE
18-60 years
Phase:
PHASE3
Brief Summary
To evaluate the outcome of visual internal urethrotomy in treating urethral strictures in males with a holmium: yttrium-aluminium garnet (YAG) laser versus when combined with intralesional injection o...
Detailed Description
Urethral strictures are one of the most common reasons for urological admissions. They are associated with urinary tract infections, bladder stones, fistulas, sepsis and possibly renal insufficiency. ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Adult male
- Presence of obstructive symptoms (moderate to severe according to IPSS scoring system i.e. \>7)
- Single urethral (stricture length \<1.5 cm) as evident on radiological studies, i.e., retrograde urethrography (RGU) and micturating cystourethrography (MCU).
- Average flow rate on uroflowmetry less than 10 ml/s
- Exclusion criteria used were:
- Complete obliteration of lumen of urethra on urethroscopy.
- Multiple strictures.
- Untreated urinary tract infection.
- Recurrent Strictures.
- Prior internal urethrotomy
- Prior urethroplasty
- Compromised upper urinary tract (increased kidney functions)
Exclusion
Key Trial Info
Start Date :
May 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 15 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06123520
Start Date
May 1 2023
End Date
October 15 2023
Last Update
November 8 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Demerdash hospital, Faculty of medicine, Ain Shams University
Cairo, Egypt