Status:

COMPLETED

A Single Group Study to Evaluate the Effects of a Vaginal Probiotic on Vaginal and Digestive Health

Lead Sponsor:

Rael

Collaborating Sponsors:

Citruslabs

Conditions:

Irritable Bowel Syndrome

Vaginal Health

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

This is a virtual single-group study that will last 12 weeks. Participants will take 1 capsule every day, with water. Questionnaires will be completed at baseline, 2 weeks, 4 weeks, and 12 weeks.

Eligibility Criteria

Inclusion

  • Women aged 18-40
  • Self-reported concerns with vaginal odor, itchiness, dryness, or discharge
  • Self-reported issues associated with bacterial Vaginosis, reporting three of the following symptoms:
  • Unusual vaginal discharge ( thin, grayish-white or milky discharge that has a strong, fishy odor)
  • Changes in vaginal odor (i.e. An unpleasant "fishy" odor)
  • Vaginal itching or irritation
  • Discomfort or burning sensation during urination
  • Self-reported symptoms associated with irritable bowel syndrome (IBS), including three of the following symptoms:
  • Abdominal pain or discomfort
  • Changes in bowel habits i.e. diarrhea, constipation, or a combination of both.
  • Bloating
  • Gas or flatulence
  • Changes in stool appearance
  • Mucus in the stool
  • Generally healthy - don't live with any uncontrolled chronic diseases
  • Willing to avoid the use of any intra-vaginal products (such as vaginal creams, gels, or medications) as well as suppositories during the study product use

Exclusion

  • Any pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders
  • Planning to undergo any procedure related to their reproductive health.
  • Started any new medications or supplements that target vaginal health or IBS in the past 3 months.
  • Anyone with known severe allergic reactions
  • Women who are pregnant, breastfeeding, or attempting to become pregnant
  • Unwilling to follow the study protocol
  • Anyone with a history of vaginal, cervical, vulvar, uterine, or ovarian cancer
  • Anyone who has changed or stopped taking hormonal birth control in the last 3 months

Key Trial Info

Start Date :

September 14 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 14 2024

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06124313

Start Date

September 14 2023

End Date

January 14 2024

Last Update

August 23 2024

Active Locations (1)

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Citruslabs

Santa Monica, California, United States, 90404