Status:
UNKNOWN
Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery
Lead Sponsor:
Tanta University
Conditions:
Aminophylline
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
The aim of this study is to evaluate the usefulness of adding aminophylline to dexmedetomidine intravenous infusion intraoperatively on oxygenation and lung mechanics in chronic obstructive pulmonary ...
Detailed Description
Bariatric surgery is considered the most effective treatment for patients suffering from morbid obesity, as it results in maintained loss of weight and clear impact on the comorbidities related to obe...
Eligibility Criteria
Inclusion
- Age from 20 to 60 years.
- Patients scheduled for laparoscopic bariatric surgery not exceeding three hours under general anesthesia.
- American Society of Anesthesiologists (ASA) class II to III.
- Patients who had no previous abdominal surgery.
- Patients with a body mass index (BMI) greater than 40 kg/m2and suffered obstructive lung disease diagnosed by pulmonary function tests (; forced vital capacity (FEV1\\FVC) \< 70%).
- Patients who are psychologically normal.
Exclusion
- Patients who refuse to participate.
- Those with arrhythmia or receiving anti-arrhythmic medications.
- Those with significant coexisting diseases (e.g. kidney, heart, liver).
- Those with known allergy to any of allocated drugs.
- Those with excessive intraoperative blood loss more than allowable amount to every patient.
Key Trial Info
Start Date :
November 11 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06125665
Start Date
November 11 2023
End Date
April 1 2024
Last Update
November 14 2023
Active Locations (1)
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1
Tanta University
Tanta, El-Gharbia, Egypt, 31527