Status:
UNKNOWN
Endometrial Cancer Screening in High-risk Populations
Lead Sponsor:
Peking University People's Hospital
Conditions:
Cancer Screening
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Endometrial cancer is one of the most common malignancies of the reproductive system. The incidence of endometrial cancer has increased in recent years. No effective, low-cost screening method for pop...
Detailed Description
The enrolled patients underwent simultaneous transvaginal ultrasound examination and microscale endometrial sampling biopsy. After enrollment, a vaginal ultrasound examination was performed to record...
Eligibility Criteria
Inclusion
- Age ≥ 45 years old
- Hypertension
- Diabetes
- Obesity (BMI ≥ 28)
- History of estrogen application without progesterone antagonism
- Polycystic ovary syndrome
- Functional ovarian tumors (ovarian tumors that secrete estrogen) before surgical treatment
- Infertility
- During tamoxifen treatment, long-term use of mifepristone (greater than 3 months)
- Abnormal uterine bleeding or vaginal discharge
- Postmenopausal vaginal bleeding or vaginal discharge
- Hereditary non polyposis colorectal cancer (HNPCC) patients over 35 years old, or patients with a family history of colorectal cancer or endometrial cancer
- Cervical cytology examination indicates atypical glandular cells (AGC)
- Previous history of ovarian cancer or breast cancer
Exclusion
- Body temperature ≥ 37.5 ℃
- Acute and subacute reproductive tract inflammation
- Suspected pregnancy
- Clearly diagnosed patients with malignant tumors of the reproductive tract
- Acute severe systemic disease
Key Trial Info
Start Date :
November 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
22000 Patients enrolled
Trial Details
Trial ID
NCT06125886
Start Date
November 15 2023
End Date
December 30 2025
Last Update
November 9 2023
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