Status:
COMPLETED
RTMS Feasibility Study on Adolescent Depression Stimulation
Lead Sponsor:
Uppsala University
Collaborating Sponsors:
Uppsala University Hospital
Conditions:
Major Depressive Disorder
Unipolar Depression
Eligibility:
All Genders
13-19 years
Phase:
NA
Brief Summary
This is an open-label study, in which all participants receives an active treatment with repetitive transcranial magnetic stimulation (rTMS) according to clinical protocol. The aim with this pilotstud...
Detailed Description
The intervention follows the identical clinical procedure used for adults. Initially, the resting motor threshold will be determined by stimulation over the motor cortex, by finding the minimal intens...
Eligibility Criteria
Inclusion
- Informed consent from parents and legal guardian
- Age 13-19 years
- Diagnosis of uni- or bipolar depression verified through a Mini International Neuropsychiatric Interview for children and adolescents (MINI-KID)
- Treatment with at least two SSRIs at an adequate dose for at least 8 weeks
Exclusion
- Epilepsy or medical history of seizures
- Conductive ferromagnetic or other magnetic sensitive metals implanted in the head or within 30 cm of the treatment coil
- Implanted device that is activated or controlled in any way by physiological signals
- Implanted medication pumps
- Intracardiac lines (even if removed)
- Active substance use disorder
- Treatment with any medication that could lower the threshold for seizures
- Usage of benzodiazepines both as prescribed drug and illegal use
- Any condition that seriously increases the risk of non-compliance or loss of follow-up
Key Trial Info
Start Date :
January 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06126198
Start Date
January 1 2022
End Date
December 31 2023
Last Update
February 4 2025
Active Locations (1)
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1
Uppsala University
Uppsala, Sweden, 75236