Status:
NOT_YET_RECRUITING
The Relationship Between NLR and PONV and ESPB
Lead Sponsor:
Qianfoshan Hospital
Conditions:
Erector Spinae Plane Block
Neutrophil to Lymphocyte Ratio
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
Brief Summary
This study aims to investigate whether preoperative NLR (Neutrophil-to-Lymphocyte Ratio) serves as a biomarker for PONV (Postoperative Nausea and Vomiting). It also examines the impact of erector spin...
Eligibility Criteria
Inclusion
- Patients undergoing elective posterior lumbar spine surgery in a prone position under general anesthesia.
- ASA classification grades I to II.
- Age between 18 and 80 years old.
- Signed the informed consent for this study.
Exclusion
- Preoperative blood transfusion.
- Uncontrolled systemic diseases.
- Patients with known uncontrolled systemic inflammatory diseases (e.g., rheumatoid arthritis, lupus, or active infections).
- Gastrointestinal system disorders.
- History of antiemetic and anticholinergic drug use.
- History of adverse reactions related to surgery, deformity correction surgeries, defined as procedures involving instrumentation across three or more levels or aimed at correcting scoliosis or kyphosis.
- Severe spinal deformities.
- Infection at the puncture site.
- Coagulation disorders.
- Long-term use of sedatives and analgesic drugs before surgery.
- Patients with mental illness or communication barriers.
- Allergic to ropivacaine.
- Participants involved in other clinical studies within the past 3 months.
- History of previous lumbar surgeries.
- Subjective unwillingness to participate in this study.
Key Trial Info
Start Date :
August 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT06127966
Start Date
August 1 2025
End Date
September 1 2026
Last Update
July 29 2025
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