Status:
ACTIVE_NOT_RECRUITING
LS-PersAFone: Pulsed Field Ablation for Long-Standing Persistent Atrial Fibrillation
Lead Sponsor:
Vivek Reddy
Conditions:
Long-standing Persistent AF
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a prospective, single-arm trial. The objective of the study is to determine the rate of atrial arrhythmia recurrence after pulmonary vein isolation (PVI) plus posterior wall isolation (PWI) us...
Detailed Description
Among patients with paroxysmal AF, numerous randomized studies have demonstrated the efficacy of catheter ablation as compared with anti-arrhythmic therapy to prevent arrhythmia recurrence. However, a...
Eligibility Criteria
Inclusion
- Age \>18 years
- Long-standing Persistent AF (\>1 year continuous AF)
- Planned for a first-ever AF ablation procedure
- Left ventricular ejection fraction \>30% (as assessed within 6 months of randomization)
Exclusion
- Prior left atrial ablation or left atrial surgery (including mitral valve surgery)
- Hypertrophic cardiomyopathy
- Major cardiac surgery within 6 months preceding the consent date
- Within 3 months preceding the consent date:
- Stroke, TIA, intracranial bleeding
- Any thromboembolic event
- Carotid stenting or endarterectomy
- Life expectancy less than one year
Key Trial Info
Start Date :
January 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06128174
Start Date
January 23 2024
End Date
November 1 2025
Last Update
February 10 2025
Active Locations (1)
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1
Mount Sinai Hospital
New York, New York, United States, 10029