Status:
RECRUITING
Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Collaborating Sponsors:
Regeneron Pharmaceuticals
Conditions:
Chronic Rhinosinusitis With Nasal Polyps
Allergic Rhinitis
Eligibility:
All Genders
18+ years
Brief Summary
During this project, the investigators want to explore in vitro changes in basal cells and the crosstalk with residing immune cells as potential pathogenic mechanisms in CRSwNP vs healthy controls by ...
Detailed Description
The investigators want to use patient and healthy control samples to study/compare the following aspects in vitro: 1. Investigate differences in epithelial and basal cell functions and differentiatio...
Eligibility Criteria
Inclusion
- Patients over the age of 18
- Males and females
Exclusion
- CRSwNP
- AR
- Smoker, or \< 1-year ex-smoker
- Underlying systematic pathology (Morbus Wegener or Churg Strauss Syndrome for example)
Key Trial Info
Start Date :
December 19 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06129552
Start Date
December 19 2023
End Date
December 1 2027
Last Update
March 22 2024
Active Locations (1)
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1
Peter Hellings
Leuven, Belgium, 3000