Status:

UNKNOWN

Echocardiographic Findings as Markers of Subclinical Cardiac Dysfunction in Patients With Non-Alcoholic Fatty Liver Disease

Lead Sponsor:

Assiut University

Conditions:

NAFLD

Eligibility:

All Genders

17-70 years

Brief Summary

The investigators aim to evaluate patients with NAFLD for early echocardiographic signs of myocardial dysfunction and if there is any correlation between the degree of steatosis or fibrosis and the de...

Detailed Description

Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD) have abnormal myocardial energy metabolism and reduced coronary functional capacity, even in the absence of risk factors for cardiovascular d...

Eligibility Criteria

Inclusion

  • all NAFLD patients who will be seen in the outpatient clinic in our hospital. Diagnosis of NAFLD will be based on clinical history and examination, imaging and fibroscan results

Exclusion

  • Children less than 16 years
  • Adults more than 70 years
  • Known advanced cardiovascular disease as:
  • advanced heart failure with reduced ejection fraction (HFrEF)
  • history of recent acute myocardial event as acute coronary syndrome
  • symptomatic chronic myocardial ischemia
  • Known or recent diagnosis of rheumatic heart disease
  • Known or recent diagnosis of congenital heart disease
  • Advanced comorbidities: advanced cancer, chronic kidney disease, advanced liver disease (decompensated cirrhosis), and advanced pulmonary disease.

Key Trial Info

Start Date :

November 20 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 20 2025

Estimated Enrollment :

165 Patients enrolled

Trial Details

Trial ID

NCT06130202

Start Date

November 20 2023

End Date

December 20 2025

Last Update

November 14 2023

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