Status:
COMPLETED
Efficacy Evaluation of Two Different Fluoride Applications
Lead Sponsor:
Ivoclar Vivadent AG
Collaborating Sponsors:
Istanbul Medipol University Hospital
Conditions:
White Spot Lesion
Eligibility:
All Genders
13-50 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to evaluate the remineralizing or preservative effect of two different fluoride-containing products. The main question aims to answer how the mineral content of the ...
Eligibility Criteria
Inclusion
- At least two active non-cavitated white spot lesions on buccal surfaces of anterior teeth or premolars (ICDAS code 1 and 2; Nyvad score 1) in two different quadrants.
- Age between 13 and 50 years
- No untreated caries lesions or periodontal disease
- No systematic disease or medication (such as antidepressants, antibiotics etc.) that affects salivary flow rate
- Subjects claimed regular brushing at least twice a day
- Subjects had to agree to keep the scheduled recall appointments for at least 1 year.
Exclusion
- Inactive non-cavitated lesions (Nyvad Score 4)
- Lesions with microcavity, cavitation, chipping or discoloration
- Lesions at buccal side of the molars
- Lesions adjacent to restoration
- Developmental white spot lesions such as enamel hypoplasia
- Pregnancy
Key Trial Info
Start Date :
February 24 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 16 2024
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT06131294
Start Date
February 24 2023
End Date
April 16 2024
Last Update
October 23 2025
Active Locations (1)
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1
Istanbul Medipo University
Istanbul, Esenler, Turkey (Türkiye), 34230