Status:
COMPLETED
Effect of Prilocaine on Motor Block During Caesarean Section
Lead Sponsor:
Cairo University
Conditions:
Spinal for Caesarean Section
Eligibility:
FEMALE
18-35 years
Phase:
PHASE4
Brief Summary
To compare the effects of using intrathecal prilocaine combined with fentanyl on duration of motor block versus that of intrathecal bupivacaine combined with fentanyl in elective caesarean section.
Detailed Description
The participants in this study will be randomized into two groups based on computer generated numbers using online randomization program (research randomizer). Upon arrival to the operating room, pati...
Eligibility Criteria
Inclusion
- Age (18-35)
- ASA II
- Singleton, full term pregnant females.
- Height (1.60-1.90) m.
- BMI \> 35 kg m-2
- Scheduled for elective caesarean section under spinal anesthesia.
Exclusion
- Patients requiring general anaesthesia
- Known or suspected coagulopathy (international normalised ratio \> 1.4), thrombocytopenia (platelet count \< 100,000).
- Known peripheral neuropathy, neurological deficits or skeletal deformities.
- Known allergy to prilocaine, bupivacaine , fentanyl.
- Infection at site of injection.
- Patients' refusal to sign informed consent
- Patients with uncontrolled cardiac morbidities (patients with tight valvular lesion, impaired contractility with ejection fraction less than 50%, heart block and arrhythmias), hypertensive disorders of pregnancy, peripartum bleeding.
Key Trial Info
Start Date :
December 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06133881
Start Date
December 1 2023
End Date
February 1 2024
Last Update
February 28 2024
Active Locations (1)
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1
Faculty of Medicine Cairo University
Cairo, Egypt