Status:

UNKNOWN

Laser Therapy for Venous Leg Ulcers

Lead Sponsor:

Ahram Canadian University

Conditions:

Venous Leg Ulcer

Varicose Ulcer

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This randomized controlled trial will evaluate the effects of high-intensity laser therapy on wound healing in patients with venous leg ulcers. Participants will be randomly assigned to receive either...

Eligibility Criteria

Inclusion

  • Male or female patients aged 18 years up to 65 years.
  • Presence of a venous leg ulcer, confirmed by clinical examination and Doppler ultrasound (venous reflux \> 0.5 seconds).
  • Ulcer size between 1 cm² and 20 cm² at screening.
  • Ulcer duration of at least 4 weeks but not more than 12 months.
  • Ankle-brachial index (ABI) ≥ 0.8, assessed by Doppler ultrasound.
  • Willing and able to provide informed consent and comply with study procedures.

Exclusion

  • Presence of an active infection in the ulcer, confirmed by clinical signs and positive culture results.
  • Osteomyelitis, diagnosed by radiographs or magnetic resonance imaging (MRI).
  • Patients with a history of uncontrolled diabetes, defined as HbA1c level \> 10%.
  • Current or planned use of systemic immunosuppressive drugs or corticosteroids during the study period.
  • Pregnant or breastfeeding women.
  • Patients with a history of malignancy or photosensitive skin disorders.
  • Prior history of skin grafting or flap surgery in the affected area within the past 3 months.

Key Trial Info

Start Date :

November 16 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2024

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06135246

Start Date

November 16 2023

End Date

August 1 2024

Last Update

November 18 2023

Active Locations (1)

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1

Outpatient clinic of faculty of physical therapy, Ahram Canadian University

Al Ḩayy Ath Thāmin, Giza Governorate, Egypt, 3221405