Status:
RECRUITING
Integrating Brain, Neurocognitive, and Computational Tools in OUD
Lead Sponsor:
University of Pennsylvania
Conditions:
Opioid Use Disorder
Eligibility:
All Genders
18-60 years
Brief Summary
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common...
Eligibility Criteria
Inclusion
- men and women with moderate to severe opioid use disorder by Diagnostic and Statistical Manual, version 5, (DSM-V) criteria on a stable (at least one week without change) dose of oral buprenorphine-naloxone or methadone. (for OUD group)
- Eligible participants will be between 18-60 years of age;
- able to read at an eighth-grade level;
- able to speak English.
Exclusion
- unable to understand or complete the tasks.
- Certain mental health conditions, including (but not limited to) bipolar I with current manic episode, schizophrenia, and schizoaffective disorder, determined by the Principal Investigator (PI) to interfere with study participation.
- moderate or severe substance-use disorder (for Healthy Controls)
Key Trial Info
Start Date :
November 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 31 2027
Estimated Enrollment :
192 Patients enrolled
Trial Details
Trial ID
NCT06136247
Start Date
November 1 2023
End Date
July 31 2027
Last Update
December 4 2025
Active Locations (1)
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1
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104