Status:

COMPLETED

Cognitive Rehabilitation in Post-COVID-19 Syndrome

Lead Sponsor:

University of Missouri-Columbia

Collaborating Sponsors:

National Institutes of Health (NIH)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Post-COVID-19 Syndrome

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS...

Detailed Description

Post-COVID-19 symptoms (PCS) cognitive symptoms require the rehabilitation community to investigate ways to: (1) reduce the functional impact of the symptoms on daily life and (2) support individuals ...

Eligibility Criteria

Inclusion

  • self-reported cognitive symptoms persisting for at least 6 weeks following COVID-19 infection (Cognitive Failures Questionnaire (CFQ) score \>43)
  • self-identified activity performance goals per the Canadian Occupational Performance Measure (COPM)
  • documented prior diagnosis of COVID-19
  • read, write, and speak English fluently
  • ability to provide valid informed electronic consent

Exclusion

  • diagnosis of severe neurological or psychiatric condition(s)
  • dementia symptoms as indicated by a score of \<23 on the Montreal Cognitive Assessment (MoCA)
  • untreated sleep apnea (≥5 on the STOPBANG)
  • prior cancer treatment
  • severe depressive symptoms (\>21 on the Patient Health Questionnaire-9)

Key Trial Info

Start Date :

February 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2025

Estimated Enrollment :

65 Patients enrolled

Trial Details

Trial ID

NCT06136871

Start Date

February 1 2024

End Date

June 30 2025

Last Update

December 2 2025

Active Locations (1)

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1

University of Missouri Department of Occupational Therapy

Columbia, Missouri, United States, 65211