Status:

UNKNOWN

CETI-ANKLE: Cetilar®️ in Patients With Ankle Injury or Chronic Trauma to the Ankle

Lead Sponsor:

Pharmanutra S.p.a.

Collaborating Sponsors:

NEA Clinical S.r.l.

Conditions:

Ankle Injury or Chronic Trauma to the Ankle

Eligibility:

All Genders

20-80 years

Phase:

NA

Brief Summary

The purpose of this study is to assess the safety, tolerability and efficacy of Cetilar®

Detailed Description

After being informed about the study, all patients giving written informed consent will undergo no more than a 1-week screening period to determine eligibility for study entry. Patients that meet incl...

Eligibility Criteria

Inclusion

  • Signing the Patient Information Sheet and Informed Consent Form
  • Patients with reduced ankle mobility caused by injury or chronic trauma to the ankle
  • Men or women aged ≥20 and ≤80 years
  • Patients who mark the pain 4 cm on a VAS
  • Patients who are willing or able to follow doctor's instructions
  • Patients not participating in other clinical trials within 30 days before the screening
  • Patients who have received sufficient explanation for this clinical trial and agreed to participate

Exclusion

  • Patients who received intraarticular injection treatment into the painful area within 3 months prior to the first visit
  • Ankle surgery in the previous six months
  • Topical NSAIDs application during the treatment period
  • BMI \> 32
  • Systemic inflammatory diseases (e.g. fibromyalgia, etc.)
  • Progressive serious medical conditions (such as cancer, AIDS or end-stage renal disease)
  • Patients with major infections in the observation period
  • Renal diseases (serum creatinine concentration more than 1.2 times the upper limit of the normal range according to the central laboratory definition reference values)
  • Liver dysfunction (serum alanine or aspartate transaminase concentrations more than 1.5 times the upper limit of normal range)
  • Patients with serious heart-related diseases such as cardiac arrest, a history of cerebral infarction, or ischemic heart disease
  • Patients who received systemic steroid treatment within 1 month prior to their first visit
  • Diabetic foot
  • Pregnant or lactating women

Key Trial Info

Start Date :

November 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2023

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06137820

Start Date

November 18 2022

End Date

December 31 2023

Last Update

November 18 2023

Active Locations (3)

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Page 1 of 1 (3 locations)

1

LLC "Altra Vita"

Tbilisi, Georgia, 0160

2

JSC "Evex Hospitals" (Caraps Medline)

Tbilisi, Georgia

3

Azienda Sanitaria Locale Viterbo | ASL Viterbo, Dipartimento di Ortopedia (Centro Coordinatore)

Viterbo, Italy, 01100