Status:
COMPLETED
Exercise Dose-response and Protein Requirements
Lead Sponsor:
University of Toronto
Conditions:
Exercise Training
Eligibility:
MALE
18-40 years
Phase:
NA
Brief Summary
Study will investigate the impact of training volume on protein metabolism to estimate the impact on daily protein requirements of endurance athletes.
Eligibility Criteria
Inclusion
- Healthy, male, endurance-trained participants who regularly run more than 40 km/week or perform endurance exercise for more than 4.5 hours/week
- Participants who have a self-reported 5-km run time of ≤23 min
- Participants who are categorized as at least "very good" based on a study by Shvartz \& Reibold (Aviat Space Environ Med. 1990 Jan;61(1):3-11), in which VO2peak is used as an index. (i.e. the participants whose VO2peak is ≥57 ml/kg/min (18-24 y), ≥54 ml/kg/min (25-29 y), ≥52 ml/kg/min (30-34 y), ≥49 ml/kg/min (35-39 y)
- Ability to complete the 16-km familiarization run on Session 2
- Aged 18-40 years old
Exclusion
- \- Inability to meet health and physical activity guidelines according to the PAR-Q+.
- Female: hormonal fluctuations associated with the menstrual cycle have been reported to alter protein metabolism during exercise and may influence specific amino acid requirements at rest; as such, the present study will test the effect of endurance exercise on protein requirements in males only to ensure a stable hormonal environment and to increase the homogeneity of the physiological response. (NOTE: we plan to test females in a future trial based off of the results obtained herein)
- Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
- Regular tobacco use
- Illicit drug use (e.g. growth hormone, testosterone, etc.)
Key Trial Info
Start Date :
November 17 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2019
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT06138951
Start Date
November 17 2017
End Date
January 1 2019
Last Update
January 5 2024
Active Locations (1)
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1
Goldring Centre for High Performance Sport at the University of Toronto
Toronto, Ontario, Canada, M5S2C9