Status:

RECRUITING

Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs

Lead Sponsor:

University of Michigan

Conditions:

Amputation

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The overall goal of this project is to model human joint biomechanics over continuously-varying locomotion to enable adaptive control of powered above-knee prostheses. The central hypothesis of this p...

Detailed Description

The overall goal of this project is to model human joint biomechanics over continuously-varying locomotion to enable adaptive control of powered above-knee prostheses. Above-knee amputees often strugg...

Eligibility Criteria

Inclusion

  • Inclusion criteria for able-bodied participants will be:
  • Aged between 18 to 65 years
  • Exclusion criteria for able-bodied, young adult participants will be:
  • Pregnant (self-report)
  • Any significant neuromuscular or musculoskeletal disorder that would interfere with the study
  • Unable to walk for 20 minutes
  • History of any cardiovascular, vestibular, or visual diseases and/or impairments that may interfere with the study
  • Cognitive deficits that would impair their ability to give informed consent or impair their ability to follow simple instructions during the experiments. In the case of screening for cognitive deficits, the consenting researcher will ask the subject if he/she has any prior history of cognitive deficits.
  • Adults with a known allergy to medical grade tape
  • Inclusion criteria for subjects with amputation will be:
  • Aged between 18 to 70 years.
  • Weigh less than 250 lbs due to limitations in the design of the prosthesis.
  • Amputee subjects will be more than two months post independent ambulation with an amputation at the transfemoral level in order to use the above-knee prosthesis.
  • Amputee subjects will have a mobility classification of K2/K3/K4 ambulators (minimum community ambulatory) and have the ability to ambulate without an assistive device beyond their prosthesis.
  • Exclusion criteria for subjects with amputation will be:
  • Weigh over 250 pounds body
  • Pregnant (self-report)
  • Any significant neuromuscular or musculoskeletal disorder that would interfere with the study
  • Inactive or physically unfit, unable to walk for 20 minutes
  • An excessively long residual limb length, and/or a non-removable cosmetic cover determined by the prosthetist performing the evaluations
  • Cognitive deficits or visual impairment that would impair their ability to give informed consent or impair their ability to follow simple instructions during the experiments. In the case of screening for cognitive deficits, the consenting researcher will ask the subject if he/she has any prior history of cognitive deficits.
  • Co-morbidity that interferes with the study (e.g., pace maker placement, severe ischemia, cardiac disease, etc.)
  • Adults unable to consent
  • Adults with a known allergy to medical grade tape

Exclusion

    Key Trial Info

    Start Date :

    December 6 2023

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 30 2028

    Estimated Enrollment :

    40 Patients enrolled

    Trial Details

    Trial ID

    NCT06138977

    Start Date

    December 6 2023

    End Date

    January 30 2028

    Last Update

    February 7 2025

    Active Locations (1)

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    Rehab Lab, University of Michigan

    Ann Arbor, Michigan, United States, 48109