Status:
RECRUITING
Study to Investigate an Association Between Brain Activity and Tidal Volume in Humans (BATMAN)
Lead Sponsor:
University Health Network, Toronto
Conditions:
Ventilation Therapy; Complications
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The communication between the lungs and the brain has drawn a lot of attention recently. Animal studies have shown that the breathing cycle is coupled with brain activity, showing that the greater the...
Detailed Description
Demonstration of a physiological relationship between tidal volume set on the ventilator and hippocampal activity measured as changes in blood-oxygenation level-dependent (BOLD) in the regions of inte...
Eligibility Criteria
Inclusion
- Patients scheduled to undergo an MRI scan of their head under general anesthesia
- Age \> 18 years
Exclusion
- Stroke, and/or brain tumor in the regions of interest that has not been diagnosed before the MRI scan
- Previous medical history of dementia
- Previous medical history of brain surgery
- Acute or chronic spinal cord Injury
- Previous Vagotomy
- Phrenic nerve injury
Key Trial Info
Start Date :
November 30 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06142773
Start Date
November 30 2023
End Date
December 31 2026
Last Update
March 6 2025
Active Locations (1)
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1
Toronto General Hospital
Toronto, Ontario, Canada, M5G 2N2