Status:

NOT_YET_RECRUITING

Acute on Chronic Liver Failure in Cirrhotic Patients at Assiut University Hospitals

Lead Sponsor:

Assiut University

Conditions:

Acute-On-Chronic Liver Failure

Eligibility:

All Genders

16-70 years

Brief Summary

ACLF is a distinct syndrome that is different from chronic progressive hepatic decompensation. In most cases of ACLF, patients present initially with clinical manifestations of a decompensating event,...

Detailed Description

Liver cirrhosis is the result of progressive fibrosis in patients with chronic liver disease of any etiology, and is associated with a poor prognosis, once hepatic decompensation starts. Cirrhosis ha...

Eligibility Criteria

Inclusion

  • all cirrhotic patients who will be admitted to our intensive care unit in our hospital meeting the criteria of defention of ACLF according to the CANONIC trial and The European Association for the Study of the Liver graded with chronic liver failure organ failure scor ( CLIF-OF )

Exclusion

  • 1- children less than 16 years 2- adult more than 70 years 3- patients with Hepatocellular carcinoma 4- patients known to be Chronic kidney disease

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT06142968

Start Date

December 1 2023

End Date

October 1 2026

Last Update

November 22 2023

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