Status:

NOT_YET_RECRUITING

Prediction of Outcome of Non Invasive Ventilation COPD Patients by Assessment of Diaphragmatic Performance

Lead Sponsor:

Assiut University

Conditions:

Acute Exacerbation COPD

Eligibility:

All Genders

40-90 years

Brief Summary

Transthoracic ultrasonographic assessment of the diaphragmatic performance as a predictor for the outcome of NIV in critically ill COPD patients with acute exacerbation.

Detailed Description

Chronic obstructive pulmonary disease (COPD) is considered a common disease worldwide, and it poses a major health and economic problem. COPD was the fifth leading cause for death in 2022 and will ra...

Eligibility Criteria

Inclusion

  • One Hundred fifty five critically ill COPD patients admitted to respiratory intensive care unit
  • Diagnosis of COPD and COPD exacerbation is fulfilled according to GOLD 2022 criteria
  • Age\>40years

Exclusion

  • Age ˂ 40 years.
  • Refusal to participate in the study.
  • Patients with morbid obesity (BMI\>40).
  • Absolute indication for intubation like coma ,hemodynamic instability, or life threatening arrhythmia.
  • Contraindication to NIV like untreated pneumothorax, pneumothorax with air leak, widespread facial burn or trauma, tracheotomy, or active upper gastrointestinal bleeding.

Key Trial Info

Start Date :

November 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 15 2027

Estimated Enrollment :

155 Patients enrolled

Trial Details

Trial ID

NCT06143150

Start Date

November 15 2023

End Date

December 15 2027

Last Update

November 22 2023

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