Status:
COMPLETED
Anterior Segment Anatomic Parameters for Risk Profiling of Primary Angle-closure Glaucoma
Lead Sponsor:
Min Ke
Conditions:
Glaucoma, Angle-Closure
Eligibility:
All Genders
30-92 years
Brief Summary
The goal of this observational study is to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG). T...
Detailed Description
We aimed to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG). This retrospective study includ...
Eligibility Criteria
Inclusion
- Primary angle-closure glaucoma （PACG) was defined as an occlusion angle with peripheral anterior synechiae and intraocular pressure (IOP) \> 21 mmHg or associated with glaucomatous optic neuropathy. The following conditions were identified as possible glaucomatous optic neuropathies, including a vertical cup-to-disc ratio ≥ 0.6, vertical cup-to-disc ratio asymmetry ≥ 0.2, optic disc haemorrhage, and visible retinal nerve fibre layer defect.
- Participants with narrow angle (NA) were selected from among patients with cataracts. NA was defined as a trabecular-iris angle (TIA) \< 15° on anterior segment optical coherence tomography, with the exclusion of glaucomatous optic neuropathy or visual field loss.
Exclusion
- (1) severe systemic disease, (2) secondary angle-closure glaucoma, (3) other ocular diseases, (4) history of intraocular surgery, and (5) unclear examination images.
Key Trial Info
Start Date :
November 22 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2023
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT06143943
Start Date
November 22 2022
End Date
February 28 2023
Last Update
November 22 2023
Active Locations (1)
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1
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China, 430071