Status:

RECRUITING

Live Birth Rate After Sperm Selection Using ZyMōt Multi (850µL) Device for Intra Uterine Insemination

Lead Sponsor:

Universitair Ziekenhuis Brussel

Conditions:

Infertility

Fertility Disorders

Eligibility:

All Genders

18-36 years

Phase:

NA

Brief Summary

This single centre interventional pilot randomized control study intends to compare two methods of sperm preparation for couples referred for Intra Uterine Insemination (IUI) procedure. Couples will b...

Detailed Description

Intrauterine insemination is a commonly used method for Medically Assisted Reproduction for patients with mild male factor infertility, anovulation, endometriosis, and unexplained infertility. It is a...

Eligibility Criteria

Inclusion

  • Fresh autologous ejaculate
  • Female age: \<37 at start of the first insemination
  • 1st IUI ever here, maximum 3 consecutive IUIs during max 6 months
  • BMI \<35
  • All natural cycles, ovulation induction allowed
  • Presence of 1 or 2 follicles at the last ultrasound
  • Regular menses (26-35 days)
  • \>1 million Total Progressive Motile Sperm Count (TPMC) after previous routine capacitation with DGC
  • Presence of at least 1 potent tube after Hyfosy

Exclusion

  • Presence of intracavitary pathology at ultrasound
  • Evidence of advance endometriosis (Grade 3 and 4)

Key Trial Info

Start Date :

January 10 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT06144268

Start Date

January 10 2024

End Date

December 1 2027

Last Update

January 30 2024

Active Locations (1)

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UZ Brussel CRG

Brussels, Belgium, 1090