Status:
RECRUITING
Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Collaborating Sponsors:
King's College London
Conditions:
COPD
Asthma
Eligibility:
All Genders
18+ years
Brief Summary
There are over 700,000 UK hospital admissions every year with lung disease symptoms. Two of the most common lung diseases contributing to these numbers are asthma and chronic obstructive pulmonary dis...
Detailed Description
In this observational study, we will be enrolling patients with diagnosed or suspected airways disease who are over 18 years old, as well as age matched healthy volunteers with no significant illness....
Eligibility Criteria
Inclusion
- Participant is willing and able to give informed consent for participation in the study
- Aged 18 years or above
- Patient: known or suspected airway disease
- Healthy volunteer: considered to be in good health with no significant comorbidity (immune disorder, cancer etc.)
Exclusion
- Known or suspected current pulmonary tuberculosis, HIV (human immunodeficiency virus), Hepatitis B Virus, Hepatitis C Virus.
- Surgery within the preceding 6 weeks
- Participants who are pregnant
- History of psychiatric, medical, or surgical disorders that in the opinion of the chief investigator may interfere with sample collection, undergo a bronchoscopy, or may compromise study completion or data collection
- Alcohol or recreational drug abuse
- Diagnosis of immunodeficiency requiring treatment
- Unable to provide written informed consent
- Unable to read or write English
- Be considered, in the opinion of the investigator, to be an unsuitable candidate for the study
Key Trial Info
Start Date :
February 8 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2029
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT06144476
Start Date
February 8 2024
End Date
August 31 2029
Last Update
February 28 2024
Active Locations (1)
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1
Guy's & St Thomas' NHS Foundation Trust
London, United Kingdom, SE1 9RT