Status:

RECRUITING

The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study.

Lead Sponsor:

Odense University Hospital

Conditions:

Peritoneal Cancer

Peritoneal Metastases

Eligibility:

All Genders

18+ years

Brief Summary

The pilot study will investigate the use of repeated FDG-PET/CT scans in 16 patients with peritoneal metastasis originating from abdominal cancers treated with Pressurized Intraperitoneal Aerosol Chem...

Detailed Description

Background: Peritoneal metastasis (PM) is a late-stage manifestation of several gastro-intestinal cancers. Conventional administrated chemotherapy has limited effect due to the peritoneal-plasma barri...

Eligibility Criteria

Inclusion

  • Patients with synchronous or metachronous histology or cytology proven GC, PC, CRC, or OC with clinical evidence of PM.
  • Patients who are eligible for and offered PIPAC at the discretion of the dedicated multidisciplinary tumor conference and subsequent out-patient evaluation at Odense PIPAC Center
  • Patients with a maximum of one extra-peritoneal metastasis at CT dated within one month of inclusion.
  • Patients in Eastern Cooperative Oncology Group performance status 0-1.
  • Patients \>18 years of age.
  • Patients must be able to give mandatory oral and written consent in Danish.

Exclusion

  • Concomitant systemic chemotherapy (bidirectional treatment).
  • Known allergies to contrast dye.
  • Any other significant disease or disorder which, in the opinion of the investigator, may either put the patient at risk because of participation in the trial, or may influence the results.

Key Trial Info

Start Date :

March 15 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT06144853

Start Date

March 15 2024

End Date

December 31 2025

Last Update

August 26 2024

Active Locations (1)

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1

Odense PIPAC Center

Odense, Funen, Denmark, 5000