Status:
COMPLETED
Shift Work Intervention Strategies for Night Shift Workers
Lead Sponsor:
Erasmus Medical Center
Collaborating Sponsors:
National Institute for Public Health and the Environment (RIVM)
Netherlands Organisation for Scientific Research
Conditions:
Shift-Work Related Sleep Disturbance
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The goal of this intervention study is to test behavioral interventions in night shift workers. The main question it aims to answer is: • Can personalized sleep or nutrition intervention strategies h...
Detailed Description
Rationale: Night work interferes with the timing of daily activities and disturbs the circadian rhythms of multiple physiological processes in the human body. This is associated with detrimental healt...
Eligibility Criteria
Inclusion
- Age 18 to 60 years.
- Work at least 4 night shifts a month on average.
- Shift workers, working rotating shifts (morning, evening and night shifts) or working predominantly night shifts. Night shift defined as work at least 1 hours between 0:00- and 6:00.
- Work at least 2 night shifts in a row
- Work ≥ 20 work hours per week.
- Having a shift duration of 6 h-12 h.
- History of ≥ 1 year of working rotating shift work or night shifts prior to the study.
Exclusion
- Taking medication that the investigator believes would interfere with the objectives of the study. For example, sleep medication, medication that interferes with glucose homeostasis, and/or anti-inflammatory drugs.
- Pregnant or have a wish to become pregnant during the study period.
- Planned surgery during the entire study period Alcohol consumption \> 21 units/week
- Severe psychiatric disease and/or any mental or physical disability that will hinder participation in the interventions
- Severe cardiovascular disease, to the discretion of the study doctor
- Having a chronic inflammatory disease, including asthma, rheumatic fever, irritable bowel disease, chronic obstructive pulmonary disease.
- Other bowel diseases, including Chron's disease and Colitis Ulcerosa.
- A disease or condition with higher bleeding risk (/risk of hemorrhage), under which a blood sample may lead to complications.
- Participation in any clinical trial including blood sampling and/or administration of substances up to 90 days before Day 01 of this study
- Recent blood donation (\<1 month prior to the start of the study)
Key Trial Info
Start Date :
February 9 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 11 2025
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT06147089
Start Date
February 9 2023
End Date
February 11 2025
Last Update
September 8 2025
Active Locations (1)
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1
Erasmus MC
Rotterdam, Netherlands