Status:

RECRUITING

An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

Lead Sponsor:

Drexel University

Conditions:

Overweight and Obesity

Eligibility:

FEMALE

14-19 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to learn about cardiovascular disease risk among adolescent girls with overweight/obesity. The main questions this trial aims to answer are: 1. Does an acceptance-b...

Detailed Description

Overweight/obesity (OW/OB) affects 14 million adolescents in the U.S. and disproportionately affects girls and racial/ethnic minorities while increasing their risk of cardiovascular disease (CVD) and ...

Eligibility Criteria

Inclusion

  • Ages 14-19
  • Gender identification as girl
  • BMI percentile ≥ 85th percentile for sex-and-age

Exclusion

  • Experience of weight loss of ≥5% of body weight in the past 6 months for any reason except post-partum weight loss
  • Having recently begun or changed the dosage of any medication known to affect appetite or body composition within the last 3 months
  • Plans to move out of the area within the next year
  • Active cancer or cancer requiring treatment in the past 2 years (except non-melanoma skin cancer)
  • Active or chronic infections (e.g., HIV or TB)
  • Active cardiovascular disease or event including hospitalization or therapeutic procedures for treatment of heart disease in the past 6 months
  • Active kidney disease
  • History of bariatric surgery
  • Lung disease: chronic obstructive airway disease requiring use of oxygen (e.g., emphysema or chronic bronchitis)
  • Diagnosed diabetes (type 1 or 2)
  • Any condition prohibiting physical activity
  • Diagnosis of an eating disorder
  • Have a mental handicap or are currently experiencing other severe psychopathology that would limit their ability to engage in the treatment program (e.g., severe depression, active psychotic disorder)
  • Recent or ongoing problem with drug abuse, alcohol abuse, or addiction
  • Currently pregnant or less than 3 months post-partum
  • Anticipation of a possible pregnancy in the next year
  • Unwillingness to report possible or confirmed pregnancies promptly during the course of the trial

Key Trial Info

Start Date :

February 14 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2028

Estimated Enrollment :

148 Patients enrolled

Trial Details

Trial ID

NCT06147973

Start Date

February 14 2024

End Date

January 1 2028

Last Update

April 10 2024

Active Locations (1)

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1

Drexel University

Philadelphia, Pennsylvania, United States, 19104