Status:
COMPLETED
A Study of Metabolic Agents Following Brain Radiation
Lead Sponsor:
Mayo Clinic
Conditions:
CNS Malignancy
Eligibility:
All Genders
18+ years
Brief Summary
This study is being done to determine if CEST magnetic resonance imaging (MRI) and FDG PET are feasible techniques to detect metabolic differences between tumor and brain in patients with a brain tumo...
Eligibility Criteria
Inclusion
- Radiographic evidence or histopathologic confirmation of CNS malignancy, with or without prior resection.
- Provide written informed consent for the current study.
- Willing to undergo at least one MRI (and possibly more at PI discretion) with proton and/or phosphorus magnetic resonance spectroscopy analysis.
Exclusion
- Vulnerable populations: pregnant or nursing women (Arm B exempt), prisoners, mentally handicapped.
- Cardiac pacemaker or artificial heart valve
- Metal plate, pin, or other metallic implant
- Intrauterine device, such as Copper-7 IUD
- Insulin or other drug pump
- Non-titanium aneurysm clips
- Previous gunshot wound
- Cochlear implant or other hearing device
- Employment history as a metalworker (had metal in eye)
- Permanent (tattoo) eye-liner
- For FDG-PET specifically: Fasting blood sugar level greater than 200mg/dl
Key Trial Info
Start Date :
December 27 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 4 2025
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT06150547
Start Date
December 27 2023
End Date
August 4 2025
Last Update
August 12 2025
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55906