Status:

NOT_YET_RECRUITING

Early Detection of Pulmonary Exacerbations in Non-cystic Fibrosis Bronchiectasis

Lead Sponsor:

Papworth Hospital NHS Foundation Trust

Collaborating Sponsors:

LifeArc

Conditions:

Non-cystic Fibrosis Bronchiectasis

Eligibility:

All Genders

18-100 years

Brief Summary

The goal of this observational study is to learn about the use of equipment to monitor health at home in participants who have non-cystic fibrosis bronchiectasis. The main question\[s\] it aims to ans...

Detailed Description

The aim of the study is to find out if data collected from home monitoring and artificial intelligence (AI) in patients with non-Cystic Fibrosis bronchiectasis can be used to detect pulmonary exacerba...

Eligibility Criteria

Inclusion

  • Under the care of the Lung Defence Clinic at Royal Papworth Hospital
  • CT confirmed diagnosis of bronchiectasis
  • Age \>/= 18 years
  • Had two or more clinician defined APEs in the year prior to enrolment
  • Typically expectorates sputum daily
  • Considered suitable for home monitoring in the opinion of the investigator
  • Able to provide written informed consent

Exclusion

  • Patients unable to provide written informed consent
  • Known cystic fibrosis
  • Lung transplant recipients or on lung transplant waiting list
  • Use of long-term oxygen therapy (LTOT) or non-invasive ventilation to manage respiratory failure
  • Patients unwilling to consent to their link anonymised data from home monitoring being used for research
  • Patients unable to use a smartphone. Patients who would like to take part but do not have a smartphone can be provided with one.
  • Patients who do not have reliable Wi-Fi at home or are unable to access public Wi-Fi at least twice per week.
  • Considered unsuitable for home monitoring in the opinion of the investigator

Key Trial Info

Start Date :

March 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2024

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06151366

Start Date

March 1 2024

End Date

October 1 2024

Last Update

February 29 2024

Active Locations (1)

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Royal Papworth Hospital

Cambridge, Cambridgeshire, United Kingdom, CB2 0AA